The aim of this study is to evaluate the efficacy of intramuscular autologus platelet rich plasma on uterine wound healing after primary cesarean section
110 pregnant female undergoing primary prelabor CS will be randomized to two groups group A)autologus PRP will be prepared from participant venous blood collected from the participants' arm into a syringe primed with ACD-A. then it will be injected into uterus after closing uterine incision . Injection sites will be selected near the incision at evenly 20 different sites group B)normal saline 0.9 will be injected into uterus after closing uterine incision . Injection sites will be selected near the incision at evenly 20 different sites.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
DOUBLE
Enrollment
134
55 participant unergoing prelabor primary CS will receive intramyometrial injection of PRP after closure of uterine incision
55 participant unergoing prelabor primary CS will receive intramyometrial injection of normal saline after closure of uterine incision
Ain Shams university maternity hospital
Cairo, Egypt
Presence of cesarean scar defect(niche)
any defect in the anterior myometrium related to scar site
Time frame: 12 weeks after CS
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