The purpose of the study is to determine whether neopterin can be dosed in the fluid of the eye's anterior chamber for patient with non-inflammatory and non-infectious ophthalmic pathology.
The study will be explained to subjects who are about to undergo ophthalmologic surgery. They will sign an informed consent and be included in the study. Urine sample will be collected specifically for the study. Eye's anterior chamber fluid will also be collected during the surgery as it is the usual practice (the sample is used for the neopterin dosage instead of being thrown away). These samples will be centrifuged, frozen in a -80° C freezer. At the end of the study, all the samples will be sent to the central Lab for the neopterin dosage analysis. Results will be communicated to the principal investigator afterward.
Study Type
OBSERVATIONAL
Enrollment
20
Eye's anterior chamber fluid and urines are sampled for posterior neopterin analysis
Centre Hospitalier Intercommunal Toulon La Seyne sur Mer
Toulon, Var, France
Detection and dosage of neopterin in the eye
HCL will detect and dose the neopterin in the eye's anterior chamber fluid
Time frame: 3 month
Neopterin concentration comparison between study values and reference value.
The reference values are standards established by the Neurobiology Lab from Lyon CHU which is the central lab that will performed the neopterin dosages.
Time frame: 3 month
False positives identification and elimination.
False positives will be determined by calibration of creatinine dosage in eye and urine samples.
Time frame: 3 month
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