The study evaluates the use of half-normal saline as an irrigant for open-irrigated catheters during atrial fibrillation ablation. By increasing the efficacy of radiofrequency energy-mediated lesion formation, half-normal saline has the potential to reduce procedural times and improved acute and long-term outcomes.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
DOUBLE
Enrollment
99
Use of half-normal saline as an irrigant for open-irrigated ablation catheters
Use of normal saline as an irrigant for open-irrigated ablation catheters
Texas Cardiac Arrhythmia Institute, St. David's Medical Center
Austin, Texas, United States
Sunnybrook Health Sciences Centre
Toronto, Ontario, Canada
total radiofrequency ablation time, and total procedure time
Time frame: intraprocedural
acute pulmonary veins, and left atrial appendage (if applicable) reconnection
Time frame: intraprocedural
freedom from atrial tachycardia/atrial fibrillation > 30 seconds without antiarrhythmic drugs
Time frame: 1 year
freedom from atrial tachycardia/atrial fibrillation > 30 seconds with or without antiarrhythmic drugs
Time frame: 1 year
long-term pulmonary veins, left atrial appendage (if applicable), and coronary sinus (if applicable) reconnection
Time frame: in case of a repeat procedure performed during the study follow-up (an average of 1 year)
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