A Trial to Evaluate the Effect of Itraconazole (ITZ), a CYP3A4 Inhibitor, on the Pharmacokinetics of Praliciguat (IW-1973) in Healthy Volunteers

Inclusion Criteria: * Subject is an ambulatory adult between 18 and 75 years old at the screening visit * Subject is in good health and has no clinically significant findings on physical examination * Body mass index is \> 18 and \< 30.0 kg/m2 at the screening visit * Women of reproductive potential must have a negative pregnancy test at the time of check-in and must agree to use protocol-specified contraception throughout the duration of the study and for 2 months after the final dose of study drug * Men must agree to use protocol-specified contraception and also to not donate sperm throughout the study and for 2 months after the final dose of study drug * Other inclusion criteria per protocol Exclusion Criteria: * Any active or unstable clinically significant medical condition * Use of any prescribed or non-prescribed medication * Other exclusion criteria per protocol