A Pilot Trial of Remotely-Supervised Transcranial Direct Current Stimulation (RS-tDCS) to Enhance Motor Learning in Progressive Multiple Sclerosis (MS)

Inclusion Criteria: * Definite MS diagnosis, progressive subtype * 9HPT score between -1.0 and -4.0 standard deviations from age-based normative data * Score of \< 7.5 or less on the EDSS (with caregiver proxy required for those with scores of 6.5 or greater)\* * Ability to understand the informed consent process and provide consent to participate in the study Exclusion Criteria: * Primary neurologic, psychiatric or other medical disorder other than MS * Use of upper extremity Botox injection within 3 months * Current use of intrathecal Baclofen * History of seizure disorder * History of head trauma or medical device in head or neck * Clinically significant abnormality on EKG * Symbol Digit Modalities Test or SDMT score ≥3.0 SD from published norms * WRAT-4 reading level below average (\<85) (estimated general intellectual function) * Skin disorder/sensitive near stimulation locations