Precise Treatment System of Biliary Malignancies Based on Special Disease Database

Xinhua Hospital, Shanghai Jiao Tong University School of Medicine10,000 enrolled

Overview

Malignant tumors of biliary system lack standard treatment and precise prognosis assessment methods. This study including 12 hospitals, collecting clinical and follow-up data of patients with biliary malignant tumors including cholangiocarcinoma and gallbladder carcinoma in recent 10 years, aim to build a special disease database, then use Bayesian networks and importance theory to establish a mathematical model to assess treatment strategies and prognosis accurately. At the same time, data on biliary malignant tumors newly treated by multicenters from 2018 to 2020 will be included to validate, adjust and refine the models to guide clinical individualized precise treatment.

Study Type

OBSERVATIONAL

Enrollment

10,000

Conditions

Cholangiocarcinoma Gall Bladder Carcinoma Biliary System Disorder

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria： * Clinical diagnosis of biliary malignancy including gallbladder carcinoma or cholangiocarcinoma verified by pathological results * Must be able to undergo surgery * Undergoing radical surgery for biliary malignancy (R0 or R1 resection) * Not complicated with other malignancy * No other treatments before and during surgery, such as radiotherapy and chemotherapy. Exclusion Criteria: * Non-primary gallbladder or cholangiocarcinoma * With distant metastasis (M1 phase) * Incomplete follow-up data * Died within 30 days after surgery.

Precise Treatment System of Biliary Malignancies Based on Special Disease Database

Overview

Conditions

Eligibility

Locations (1)

Outcomes

Primary Outcomes

Central Contacts