The study evaluates the use of half-normal saline as an irrigant for open-irrigated catheters during left ventricular outflow tract ventricular arrhythmias ablation. By increasing the efficacy of radiofrequency energy-mediated lesion formation, half-normal saline has the potential to reduce procedural times and improved acute and long-term outcomes.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
DOUBLE
Enrollment
50
Use of half-normal saline as an irrigant for open-irrigated ablation catheters
Use of normal saline as an irrigant for open-irrigated ablation catheters
University of Colorado Hospital
Aurora, Colorado, United States
Texas Cardiac Arrhythmia Institute, St. David's Medical Center
Austin, Texas, United States
total radiofrequency ablation time, and total procedure time
Time frame: intraprocedural
acute success
elimination of the VAs, or \<10 morphologically similar PVCs during a 15-minute waiting period
Time frame: intraprocedural
long-term success
elimination of the VAs, or a reduction of \>75% of the PVC burden associated with marked improved in symptoms
Time frame: 1 year
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