Cytoreductive surgery with intraperitoneal chemotherapy is one of the most important treatments for patients with colorectal cancer and peritoneal metastasis. For the best survival rates, complete removal of all metastatic lesions is the most important part of treatment, and various surgical procedures are required for the complete cytoreduction. Therefore, the postoperative morbidity rates are higher than those of localized colon cancer surgeries and patients can experience a prolonged recovery period and deterioration of physical activities over a long period. The aim of this study is to investigate the change of quality of life after cytoreductive surgery and intraperitoneal chemotherapy for colorectal cancer.
Study Type
OBSERVATIONAL
Enrollment
50
Cytoreductive surgery and intraperitoneal chemotherapy for colorectal cancer or pseudomyxoma peritonei. Either early postoperative intraperitoneal chemotherapy (EPIC) or hyperthermic intraperitoneal chemotherapy (HIPEC) is used for intraperitoneal chemotherapy.
Kyungpook National University Chilgok Hospital
Daegu, South Korea
Brief pain inventory (BPI)
Pain recovery after cytoreductive surgery and intraperitoneal chemotherapy
Time frame: Changes from baseline pain scores at postoperative 12 months
European Organisation for Research and Treatment of Cancer (EORTC) Quality of life questionnaire (QLQ)-C30
Qualify of life questionnaire for cancer patients
Time frame: preoperative, postoperative 3 months, postoperative 6 months, postoperative 12 months, postoperative 24 months
EORTC QLQ for colorectal cancer
Quality of life questionnaire for patients with colorectal cancer
Time frame: preoperative, postoperative 3 months, postoperative 6 months, postoperative 12 months, postoperative 24 months
Short-form(SF)-36
Global measure of health-related quality of life
Time frame: preoperative, postoperative 3 months, postoperative 6 months, postoperative 12 months, postoperative 24 months
Postoperative morbidity
Incidence and degree of surgical and medical complications after surgery
Time frame: 90 days after surgery
Postoperative mortality
Incidence of postoperative mortality
Time frame: 90 days after surgery
Postoperative recovery
Duration of hospital stay after surgery
Time frame: 150 days after surgery
Brief pain inventory (BPI)
Pain recovery after cytoreductive surgery and intraperitoneal chemotherapy
Time frame: preoperative, postoperative 3 months, postoperative 6 months, postoperative 24 months
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