A New Prognostic Scoring System for Spontaneous Ruptured Hepatocellular

Huazhong University of Science and Technology129 enrolled

Overview

Develop a new scoring system for HCC patients with tumor rupture.

There has been no special prognostic scoring system for HCC patients with tumor rupture in the literature. In this work, we obtained all survival risk factors of ruptured HCC patients who underwent partial hepatectomy using multivariable Cox regression analysis. Furthermore, we develop and validate a new postoperative scoring system for patients with spontaneous HCC rupture based on the these results.

Study Type

OBSERVATIONAL

Enrollment

129

Conditions

Rupture, Spontaneous

Interventions

Liver resectionPROCEDURE

Partial hepatectomy comprised single or multiple hepatic resections aiming at excising all visible malignant tissue.

Eligibility

Sex: ALLMin age: 15 YearsMax age: 75 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Received partial hepatectomy; with Child A or B liver function. Exclusion Criteria: * Without complete data；loss of follow-up; had reveived repeated transcatheter arterial chemoembolization before rupture; received non-radical resection.

Outcomes

Primary Outcomes

Overall survival

Overall survival after partial hepatectomy

Time frame: 3 years

Secondary Outcomes

Disease-free survival

Recurrence-free survival after partial hepatectomy

Time frame: 3 years

Data from ClinicalTrials.gov

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