Drug-coated Balloon Angioplasty for Patients With Symptomatic Vertebral Artery Stenosis

Inclusion Criteria: * Age 18 years or older * Patients presenting with posterior circulation transient ischemic attack or nondisabling stroke in the previous 6 months * Vertebral artery origin stenosis resulting from presumed atheromatous disease with stenosis ≥50% * Lesion length of the stenosis \>5mm. * Angioplasty can be performed within two weeks after randomization * Female subjects of childbearing potential have a negative pregnancy test. * Signed informed consent prior to entering study Exclusion Criteria: * Potential cause of TIA or minor stroke other than stenosis in a vertebral artery (e.g. atrial fibrillation) * Life expectancy shorter than 2 years * Vertebral artery stenosis caused by dissection * Vertebral stenting felt to be technically impracticable * Previous stenting in randomized artery * Pre-morbid modified Rankin scale score of greater than 3 * Currently participating or previously participated in any investigational drug or device study within 6 months.