The Value of Placental Vascularization and Placental Volume in Pregnancy in APLS

Aljazeera Hospital100 enrolled

Overview

Antiphospholipid antibodies are autoantibodies directed against phospholipid-binding proteins. Among these groups of antibodies, lupus anticoagulant (LA) and anticardiolipin antibodies (aCL)

APLS can be primary when no evidence of autoimmune disease is found, or secondary to autoimmune processes like systemic lupus erythematous (SLE) in a 40% of the cases.

Study Type

OBSERVATIONAL

Enrollment

100

Conditions

Antiphospholipid Syndrome in Pregnancy

Interventions

Ultrasound with Doppler and 3D technologyDIAGNOSTIC_TEST

ultrasound will be made to pregnant females in 3rd trimester with doppler and 3D technology

Eligibility

Sex: FEMALEMin age: 18 YearsMax age: 40 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * Singleton pregnancy. * Gestational age of 34-37 weeks. * Pregnant women with antiphospholipid syndrome Exclusion Criteria: * Twin or multiple pregnancies. * Congenital fetal anomalies. * Gestational age of less than 34. * Gestational age of more than 37. * Women with placental or umbilical artery anomalies. * Antepartum hemorrhage (placental abruption, placenta previa and vasa previa). * Posterior placenta. * History of rupture of membrane. * Patient refusal or fall outs.

Locations (1)

Algazeerah

Giza, Egypt

RECRUITING

Outcomes

Primary Outcomes

The number of participants who will have impaired placental doppler indices

Time frame: within 2 months

Central Contacts

Mahmoud Alalfy

CONTACT

01002611058 mahmoudalalfy@ymail.com

Data from ClinicalTrials.gov

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