A Study of CS1001 in Subjects With Relapsed or Refractory Classical Hodgkin Lymphoma

Inclusion Criteria: 1. Subjects with histologically confirmed cHL at study site. 2. Relapsed or refractory cHL that failed at least two lines of systemic therapy. 3. ECOG PS of 0-2. 4. Subjects with at least one measurable lesion at baseline. 5. Subjects treated by prior anti-cancer therapy whose toxicity resolved to baseline or =\< Grade 1 according to Common Terminology Criteria for Adverse Events (CTCAE) v4.03 6. Subjects who agree to use highly effective contraception. Exclusion Criteria: 1. Nodular lymphocyte predominant Hodgkin lymphoma or grey zone lymphoma. 2. Primary site in central nervous system (CNS) or CNS involvement. 3. Subjects currently participating in other clinical studies or use of any investigational drug within 4 weeks prior to the first dose of CS1001. 4. Subjects who had systemic corticosteroid or any other immunosuppressive therapy within 14 days prior to the first dose of CS1001. 5. Subject who had chemotherapy, immune therapy or biological therapy as systemic anti-cancer treatment within 28 days prior to the first dose of CS1001. 6. Receipt of traditional medicinal herbal preparations within 7 days prior to the first dose of CS1001. 7. Known history of human immunodefiency virus (HIV) infection and/or acquired immune deficiency syndrome. 8. Subjects with active Hepatitis B or C infection. 9. Subjects with active tuberculosis infection. 10. Subjects who received prior therapy with anti-PD-1, anti-PD-L1 or anti CTLA-4 monoclonal antibody. 11. Female subjects who are pregnant or breast-feeding. For more information regarding trial participation, please contact at cstonera@cstonepharma.com