NCT03506516 - Does Mixing Alcoholic Drinks Make Hangover Worse? | Crick

Overview

Does mixing alcohol make hangover worse?

Hangover is the most commonly occurring morbidity associated with heavy drinking. Our aim was to test the hypothesis that mixing alcoholic drinks as compared to drinking one type of alcohol only (beer, wine or spirits) associate with a higher alcohol intake and worse hangover.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

HEALTH_SERVICES_RESEARCH

Masking

TRIPLE

Enrollment

35

Conditions

Alcohol-Related Disorders

Interventions

Mixing alcoholDIETARY_SUPPLEMENT

Alcoholic beverages, different types

Single type alcoholDIETARY_SUPPLEMENT

Alcoholic beverages, different types

Eligibility

Sex: ALLMin age: 18 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * written and oral consent * minimum 18 years old * participating in Danish Health Research Retreat in Turkey 2016 * will consume alcoholic beverages Exclusion Criteria: * underage * will not consume alcoholic beverages

Outcomes

Primary Outcomes

Acute Hangover Severity Scale (AHSS)

AHSS is a 12-item alcohol hangover measurement tool recommended for application in hangover research with a predictive validity of 92.4 %, significantly higher than that of other hangover scales (Penning et al., 2012). Alcohol hangover was measured thrice the day after drinking; in the morning immediately after waking up, at midday, and in the afternoon. The individual participant assessed his or her own hangover the day after.

Time frame: Baseline

Secondary Outcomes

Number of drinks

Total number of drinks defined as 12 g of alcohol consumed during evening

Time frame: Baseline

Acute Hangover Severity Scale (AHSS) 2

AHSS is a 12-item alcohol hangover measurement tool recommended for application in hangover research with a predictive validity of 92.4 %, significantly higher than that of other hangover scales (Penning et al., 2012). Alcohol hangover was measured thrice the day after drinking; in the morning immediately after waking up, at midday, and in the afternoon. The individual participant assessed his or her own hangover the day after.

Time frame: after 4 hours

Acute Hangover Severity Scale (AHSS) 3

AHSS is a 12-item alcohol hangover measurement tool recommended for application in hangover research with a predictive validity of 92.4 %, significantly higher than that of other hangover scales (Penning et al., 2012). Alcohol hangover was measured thrice the day after drinking; in the morning immediately after waking up, at midday, and in the afternoon. The individual participant assessed his or her own hangover the day after.

Time frame: after 8 hours