Nutritional Approaches in Multiple Sclerosis

Inclusion Criteria: * Existing health insurance, so that in case of random findings these can also be clarified * Patients with relapsed-remitting MS according to the MS diagnostic criteria according to McDonald 2010 * Age 18-65 * Consent ability and written consent * BMI between 19 and 45 kg / m2 * EDSS \<4.5 * Stable immunomodulatory therapy or no immunomodulatory therapy\> 6 months before confinement * In the last 2 years ≥ 1 relapse or within the last 2 years ≥ 1 new T2 lesions or ≥ 1 contrast-sensitive lesion in MRT * Consent that possible random findings are reported Exclusion Criteria: * Initiation or modification of immunomodulatory therapy during the study * Cortisone treatment in the last 30 days before enrollment * Relapse in the last 30 days before enrollment * Insulin-dependent diabetes mellitus (type I) * Intake of Omega 3 fatty acids (DHA, EPA) - more than 1 g / day * Significant cognitive impairment, clinically relevant or progressive disease (e.g., liver, kidney, cardiovascular system, respiratory tract, vascular system, brain, metabolism, thyroid) that could affect the course of the study * Malignant disease * Simultaneous participation in an interventional study or participation in an interventional study in the last two months before study inclusion * Clinically relevant addiction or substance abuse disorder (defined as alcohol, drug and drug abuse) * Nicotine consumption of \> 5 cigarettes per day and no willingness to stop consumption during therapeutic fasting. * Insufficient mental possibility of cooperation * Eating disorder * Kidney stones * Known metabolic disorders (e.g., fatty acid oxidation disorders, ketolysis / ketogenesis or glucogenesis disorder, hyperinsulinism (e.g., nesidioblastoma), pyruvate carboxylase deficiency) * Therapy with oral anticoagulants (e.g., Marcumar) * Pregnancy and breast feeding period * Suspected lack of compliance * Performing of a diet for weight reduction * Special diet for medical reasons * Change of the body weight of more than 5 kg within one month before the start of the Intervention * Medical, psychiatric or other conditions that restrict the patient's following abilities: to interpret the study information, to give informed consent, to adhere to the rules of the protocol, or to complete the study * Contraindications to MRT examinations \[persons with metallic implants (e.g., intracranial metal clips) and carriers of electronic devices (e.g., pacemaker) or persons with claustrophobia\]