Bipolar disorder is a severe psychiatric illness with chronic course and it is associated with high risk of relapse and hospitalisation, and many patients do not recover to their previous psychosocial functioning. Major reasons for poor outcomes are delayed intervention for prodromal mood and behavioural symptoms as well as incomplete treatment responses. Current diagnostic approaches used to assess mood symptoms rely on symptom-based categories, which lack sensitivity to detect subtle mood and behavioural changes. Therefore, the ability to better characterizing bipolar patients may allow to detect possible differences in the illness activity. On the other hand, there is a growing interest in the potential use of mobile technologies such as mobile apps, smartphone and internet in psychiatric care. Some projects have been testing the potential benefits of mobile apps to assess and treat individuals at-risk or suffering from mood and bipolar disorders, using online signs and symptoms monitoring, yet to the investigators knowledge, none of them have integrated a dimensional approach in a smartphone app to assess mood and behavioural alterations and bipolar illness activity, including subjective and objective data (e.g. physical activity, social activity, etc.). In this feasibility study the investigators will evaluate the potential relevance of Toi Même app to self-monitoring mood and behavioural changes in bipolar patients with different mood phases compared to the gold-standard mood rating tools used in clinical practice. All patients will be followed for 3 months, with outcome assessments after 2 weeks, after 1 month, 2 months and after 3 months.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
SUPPORTIVE_CARE
Masking
NONE
Enrollment
36
Toi Même self-monitoring smartphone application plus treatment as usual which includes pharmacological and/or psychological treatment.
Nightingale Hospitals Paris - Clinique du Château
Garche, France
Centre Thérapeutique et Preventif de Jour - Troubles Bipolaires (Clinique Bellevue)
Meudon, Île-de-France Region, France
Centre Hospitalier Sainte Anne
Paris, Île-de-France Region, France
Severity of depressive symptoms
Changes in depressive symptoms measured using the Montgomery-Asberg Depression Rating Scale during the 3 months study period.
Time frame: 3 months study period
Severity of manic symptoms
Changes in manic symptoms measured using the Young Mania Rating Scale during the 3 months study period.
Time frame: 3 months study period
Self-rated depressive symptoms
Differences in self-rated depressive symptom using the Quick Inventory of Depressive Symptomatology (QIDS) during the 3 months study period.
Time frame: 3 months study period
Self-rated manic symptoms
Differences in self-rated manic symptoms using the Altman Mania Self-Rating Scale (ASRM) during the 3 months study period.
Time frame: 3 months study period
Activation levels
Changes in levels of activation measured using the scale Multidimensional Assessment of Thymic States (MAThyS) during the 3 months study period.
Time frame: 3 months study period
Treatment adherence
Differences in treatment adherence using the 10-item Medication Adherence Rating Scale (MARS) during the 3 months study period.
Time frame: 3 months study period
Functional impairment
Differences in functional impairment using the Functioning Assessment Short Test (FAST) during the 3 months study period.
Time frame: 3 months study period
Movement behavior
Differences in movement behavior using the smartphone motion sensors during the 3 months study period.
Time frame: 3 months study period.
Completion rate
Differences in the completion rate of app self-assessment questionnaires.
Time frame: 3 months study period.
Patient acceptance
Patient acceptance rate measured by a questionnaire
Time frame: 3 months study period.
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