Effects of the Physical Fitness on Serum Klotho Levels in Healthy Population

Universidad Europea de Madrid85 enrolled

Overview

Exercise program in serum Klotho levels

This study aims to analiyze the effects of acute exercise in serum Klotho levels attending physical fitness in healthy population

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

OTHER

Masking

SINGLE

Enrollment

Conditions

Healthy Population

Interventions

plyometric exerciseOTHER

acute plyometric exercise

Aerobic exerciseOTHER

acute aerobic exercise

Eligibility

Sex: MALEMin age: 18 YearsMax age: 45 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * healthy people between 20 and 45 years old Exclusion Criteria: * acute and chronic disease, people who take medication and supplements, smoker.

Locations (1)

Escuela de Doctorado e Invesitgacion, Universidad Europea

Madrid, Villaviciosa de Odon, Spain

Outcomes

Primary Outcomes

Change in serum Klotho levels

Change from baseline to acute exercise session

Time frame: Baseline and one hour

Secondary Outcomes

Change in Cardiorespiratory Fitness VO2max

For this Variable All people Will perform a exercise test on treadmill (Tecnhogym run race 1400HC; Gambettola, Italy), in this way we determinate the VO2max. Through the modifies Balke protocol. The gas Exchange data Will measured breath by breath using open circuit spirometry and specific face mask for Fitmate, Cosmed; Vmax 29C, Sensormedics machine.

Time frame: Baseline

Change in Body Composition

The age in years; height in centimeters (tallimeter Ano Sayol SL, Barcelona, Spain); weight in kilograms (Inbody 720, Microcaya) and we can derive from this data the variable of Body Mass Index (BMI) calculated as weight (kg)/height (m2).

Time frame: Baseline

Change in Body Composition, Body muscle mass Index

For determinate this variable of the body composition will be use a Dual Densitometry X-Ray (DXA) (Hologic QDR Discovery, Bedford, MA, USA)

Time frame: Baseline

Change in Body Composition, % of Fat Mass

For determinate this variable of the body composition will be use a Dual Densitometry X-Ray (DXA) (Hologic QDR Discovery, Bedford, MA, USA)

Time frame: Baseline

Change in Body Composition, Total Muscle Mass

For determinate this variable of the body composition will be use a Dual Densitometry X-Ray (DXA) (Hologic QDR Discovery, Bedford, MA, USA)

Time frame: Baseline

Data from ClinicalTrials.gov

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