The purpose of this study is to evaluate the effect of probiotics on the gut microbiome of infants with jaundice.
This study aims to examin the impact of probiotics administration during the process of infants jaundice treatment and recovery phase.the recovery phase.Birth,7 days,14 days and 42 days data will be collected and put into analysis to provide some suggestions on the probiotics use in the clinical for the infants with jaundice.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
SINGLE
Enrollment
30
the patients in this arm will receive probiotics blend of Bifidobacterium longum, Lactobacillus acidophilus, Enterococcus faecalis with does of 1.5\*10\^7CFU for 2 weeks
Shanghai 10th People's Hospital
Shanghai, China
RECRUITINGchange from birth,7 days,14 days on gut microbiome at 42 days by 16S rRNA
change of the gut microbiome will be calculated at 42 days in comparison with birth,7 days,14 days
Time frame: 42 days
change from birth on gut microbiome at 7 days by 16S rRNA
change of the gut microbiome will be calculated at 7 days in comparison with baseline
Time frame: 7 days
change from birth and 7 days on gut microbiome at 14 days by 16S rRNA
change of the gut microbiome will be calculated at 14 days in comparison with birth and 7 days
Time frame: 14 days
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