Functional ICUS in Uganda and Their Survival Outcomes

Makerere University367 enrolled

Overview

Aim of the study is to describe the functional characteristics of Icus in Uganda and their @8-day patient characteristics it is a prospective cohort study .All Icus in Uganda will be included and their admitted patients followed upto 28 days in the ICU for mortality

Intensive Care units are specialized units with expertise to provide organ support for the critically ill patients. There's a growing global burden of critical illness especially in the low-income coun-tries where critical care services are limited. Despite advances in critical care, the mortality in Uganda remains very high, with sepsis and trauma as the major contributors. There's paucity of literature regarding ICUs characteristics, disease burden and patient characteristics which could be contributing to the high mortality. Objectives To describe the functional characteristics of the ICUs in Uganda. To determine the ICU mortality of critically ill patients in Uganda. To determine the risk factors of mortality of patients admitted in the ICU Methods A prospective cohort study will be carried out in all ICUs in Uganda. All new patients in the ICUs will be recruited into the study. Data will be collected onto two separate questionnaires, one for patient characteristics and the second for ICU functional characteristics. The patient's data will be collected within the first 24 hours and patients will be followed up for death\\discharge within 28 days in the ICU. The data will be collected from the patients' charts and entered into Epidata.

Study Type

OBSERVATIONAL

Enrollment

367

Conditions

Critical Illness

Eligibility

Sex: ALL

Medical Language ↔ Plain English

Inclusion Criteria: All new patients admitted to Uganda's Intensive Care Units ICUs in Uganda whose unit heads verbally consent to participate in the study. Exclusion Criteria: Patients transferred in from another unit will not be re recruited. ICUs that don't consent to the study.

Locations (1)

Atumanya Patience

Kampala, Uganda

Outcomes

Primary Outcomes

28 day mortality

Total number of patients who died during the study period within 28 days over the total number recruited, and a survival analysis will be plowed on a Kaplan Meier

Time frame: 3 months

functional characteristics of ICUs in Uganda

outcome measure will be descriptive, that is interms of ICU location(urban or rural), staffing (nurse to patient ratio), infrastructure(floor space cm2), monitoring equipment, services rendered(organ support), and the ICU operation models(closed versus open) will be assessed for association with patient outcome

Time frame: 3 months

Secondary Outcomes

factors associated with mortality

Age ( years), sex, indication for admission, length of ICU stay(days), comorbidities, HIV and HAART status, Mechanical ventilation(days) and length on ICU stay(days), ICU final diagnosis, Ino-tropic/vasopressor use, Sedation, NEWS score will be run in univariate and multivariate to assess association with mortality.

Time frame: 3 months

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.