The Effect of Multiple-Task Training in Patients With Multiple Sclerosis

Gazi University39 enrolled

Overview

The Activities of Daily Living requires the ability to perform multiple activities at the same time, not just the motor or cognitive activity. When many tasks are performed at the same time, the attention capacity is effectively used and attention is shared according to the difficulty and priority of the tasks. There is evidence that patients with Multiple Sclerosis (MS) have reduced performance during multitasking. In this study, the investigators aim to investigate the effect of multitasking training on balance, mobility, upper extremity performance and cognitive functions in patients with MS.

Patients with MS between 0-1,5 score according to the Extended Disability Status Scale (EDSS) will be included in the study. The balance, mobility, upper extremity performance, the cognitive function will be evaluated twice. The study was designed as a prospective, randomized controlled study. The patients will be randomly assigned to three groups, the "multi-task training (MT)" group, the "single task training (ST)" group, and "control" group. The training will be twice a week for 6 weeks. Statistical analyses will be performed using the SPSS software version 15 (SPSS Inc. Chicago, IL, USA). The pre-training and post-training measurements of groups will be compared with the Wilcoxon Test. The significance level was set at p\< 0.05

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Multiple Sclerosis

Interventions

Multi-task trainingOTHER

In the multitasking training group, a second motor task in the first two weeks, a cognitive task in the third and fourth week, both motor and cognitive tasks in the last two weeks will be added to these 10 different motor tasks.

Single task trainingOTHER

An exercise program consisting of 10 different motor tasks will be implemented in a single task training group.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 65 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Participants who are ambulatory and volunteer to participate to the study, in a stable phase of the disease, without relapses in the last 3 month, with an EDSS between 0-1,5. Exclusion Criteria: * Participants who have orthopedic, vision, hearing, or perception problems * Patients who have any cardiovascular or pulmonary disease in which exercise is contraindicated

Locations (1)

Gazi University

Ankara, Turkey (Türkiye)

Outcomes

Primary Outcomes

Mobility

Timed Up and Go Test

Time frame: ten minutes]

Modified Sensory Organization Test

The Modified Sensory Organization Test, which is performed using computerized posturography, measures postural sway in response to 4 different sensory conditions is measured using a force platform.

Time frame: Fifteen minutes]

Upper extremity function

9-Hole Peg Test

Time frame: ten minutes

cognitive function

The Brief Repeatable Battery of Neuropsychological Tests

Time frame: thirty minutes

Secondary Outcomes

Physical Activity

International Physical Activity Questionnaire- Long version

Time frame: ten minutes

Fatigue Impact

Fatigue impact scale consists of forty questions and evaluates the effects of fatigue on the 3 dimensions of daily life activities; cognitive function, physical function and psychosocial function. Each question is graded between 0 (no problem) and 4 (maximum problem).

Time frame: five minutes

Fatigue Severity

In the Fatigue Severity Scale (FSS), participants are asked to rate their fatigue level between 1 and 7 in the 9 statements (including motivation, exercise, physical functioning, carrying out duties, and interfering with work, family, or social life) during the last week.

Time frame: Five minutes

Data from ClinicalTrials.gov

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