In this prospective randomized clinical trial we plan to compare two fertilization method which are widely used during in vitro fertilization (IVF) treatment. Outcome of conventional IVF and intracytoplasmic sperm injection (ICSI) treatment will be compared in this study.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
TREATMENT
Masking
TRIPLE
Enrollment
600
Oocytes are fertilized by conventional in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI)
Semmelweis University First Department of Obstetrics and Gynecology
Budapest, Hungary
Fertilization rate
Number of oocytes fertilized
Time frame: 18 hours after insemination
Embryo quality
Number and quality of blastomeres, amount of fragmentation, embryo grade
Time frame: 36 and 72 hours after fertilization
Implantation rate
Number of embryos implanted (/number of embryos transferred)
Time frame: 4 weeks after embryo transfer
Clinical pregnancy rate
Number of clinical pregnancies (/No. of embryo transfers)
Time frame: 4 weeks after the embryo transfer
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