Prospective Tissue Collection Research Protocol

Inclusion Criteria: * Aged ≥ 18 years * Written informed patient consent for tissue, blood collection or leukapheresis, including storage and manipulation. * Suspected or confirmed diagnosis of selective solid tumours with either primary, recurrent or metastatic disease. * Patient is scheduled for surgical excision and/or collection of multiple tissue samples via image or device guided biopsy, has a superficial skin or subcutaneous lymph node metastasis that can be safely accessed for the purposes of the study. * Haemoglobin(Hb) ≥ 10g/dL without transfusion support for at least 3 weeks (for patients donating whole blood). White cell count ≥ 3 x 10\^9/L (for patients donating whole blood). * For selected solid tumours and leukapheresis procedure additional inclusion criteria apply. Exclusion Criteria: * Clinical status precludes surgical removal of, or collection of multiple biopsies from, accessible tumour tissue. * Inadequate peripheral venous access precluding collection of blood. * Pregnant or breastfeeding women. * Known/laboratory confirmed diagnosis of an active infectious disease to include Hepatitis B and C, human immunodeficiency virus infection (HIV1/2), Human t-lymphotropic virus (HTLV I/II) and syphilis. * Patients who are currently participating in a clinical trial involving an unlicensed medical product. * Patients who have received any cytotoxic therapy (including investigational products) within three weeks prior to tissue procurement. * Patients receiving immunosuppressive treatments or who require regular treatment with steroids at a dose higher than prednisolone 10 mg/day (or equivalent). * Any medical reason why, in the opinion of the investigator, the patient should not participate in this study. * For selected solid tumours and leukapheresis procedure additional exclusion criteria apply.