to examine if a natural daytime variation in progesterone levels may explain parts of the inconsistent findings from studies reporting divergent results concerning this matter and will be carried out by several blood samples from the same patient during the day of ovulation triggering.
The impact of the progesterone level at the end of the follicular phase in stimulated IVF/ICSI cycles and its effect on the pregnancy rate and oocyte quality is controversial, which arises from conflicting results in retrospective studies and meta-analyses. This study is assumed to examine if a natural daytime variation in progesterone levels may explain parts of the inconsistent findings from studies reporting divergent results concerning this matter and will be carried out by several blood samples from the same patient during the day of ovulation triggering. If variation is present, the impact of variation on the developing oocyte and embryo quality will be estimated by embryo quality indicators.
Study Type
OBSERVATIONAL
Enrollment
30
The potential gain for medical caretakers and patients would be a certainty if the progesterone level is affected by variations during daytime
IVI Middle East Fertilty Clinic
Abu Dhabi, United Arab Emirates
The variation of serum progesterone around the ovulation triggering in IVF-cycles
the circadian secretion-pattern of progesterone during early follicular phase of normal cycling females
Time frame: 6-8 months
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