This study is a non-interventional, specimen collection translational study to evaluate vitamin C levels in the peripheral blood of Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome (MDS), or Chronic Myelomonocytic Leukemia (CMML) patients.
It has previously been established that hematological cancer patients with myelodysplastic syndrome (MDS) or acute myeloid leukemia (AML) often exhibit severe vitamin C deficiency from a cohort of patients in Copenhagen. In this study, the investigators aim to determine if those results are conserved in another population/geographical location.
Study Type
OBSERVATIONAL
Enrollment
50
Peripheral blood collection for the measurement of ascorbic acid levels and banking of plasma and buffy coat for future resrearch.
Cancer and Hematology Centers of Western Michigan
Grand Rapids, Michigan, United States
Metro Health - University of Michigan Health
Wyoming, Michigan, United States
Peripheral blood ascorbic acid levels
The level of ascorbic acid
Time frame: 1 year
Evaluation of human endogenous retroviral sequences (HERVs) expression
Time frame: 1 year
Evaluation of 5-methylcitosine (5-mC) and 5-hydroxymethylcytosine (5-hmC) levels
Time frame: 1 year
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