Block Duration After Spinal Block and iv Dexamethasone.

Eric Albrecht50 enrolled

Overview

It has been largely demonstrated that iv dexamethasone prolongs the duration of analgesia after peripheral nerve block. However, data are missing regarding the duration of analgesia after spinal block. The objective of this randomized controlled double-blinded trial is to assess whether intravenous dexamethasone administered after a spinal block, before the surgery would prolong sensory block characteristics without impacting the motor block duration.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

TRIPLE

Enrollment

Conditions

Postoperative Pain Lower Limb Injury

Interventions

DexamethasoneDRUG

Intravenous injection of 0.15 mg/kg of dexamethasone before the surgery.

NaCl 0.0308 MEQ/ML Injectable SolutionDRUG

Intravenous injection of NaCl 0.9% before the surgery.

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Patient with ASA I-III status ; * Patient scheduled for an osteosynthesis surgy of the lower limb Exclusion Criteria: * Polytrauma patient * Pregnancy * Contraindication to spinal anesthesia * Contraindication to dexamethasone administration * Patient with chronic pain

Locations (1)

Centre Hospitalier Universitaire Vaudois and University of Lausanne

Lausanne, Canton of Vaud, Switzerland

Outcomes

Primary Outcomes

Duration of sensory block (minutes)

Time interval between injection of the local anaesthetic and the regression of 2 dermatoma, compared to the highest dermatoma reached