Process Optimization of Preoperative Biliary Drainage in Patients With Malignant Obstructive Jaundice

Inclusion Criteria: * Patients who meet the following four criteria are included into the study: 1. Preoperative clinical diagnosis of hilar cholangiocarcinoma, distal bile duct cancer, periampullary cancer without distant metastasis or peripheral vascular invasion, and plan for radical surgery; 2. Serum total bilirubin is higher than 51 umol/l; 3. Age is older than 18 and younger than 80 years old; 4. Sign in informed consent to receive preoperative PTBD, ENBD, EBS or without PBD. Exclusion Criteria: * If any of the following items are met, the subject cannot enter the study. 1. Incorporate severe mental illness, severe heart, lungs and kidneys disease, etc., and be unable to tolerate surgery; 2. Malignant obstructive jaundice caused by metastatic tumors; 3. Pregnancy or lactation women.