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Amniotic Membrane for Recurrent Macular Hole

N/AUnknownNCT03528122
Minia University20 enrolled

Overview

Macular hole surgery were tried by different surgeons using many techniques with different successes but still there were many recurrences. In this study the investigators try to close these distinct types including recurrent holes using pre-prepared amniotic membrane.

It is an interventional study of using amniotic membrane graft for closure of macular hole associated retinal detachment in patient who had a previous failed macular surgery.

Study Type

INTERVENTIONAL

Allocation

NA

Purpose

TREATMENT

Masking

NONE

Enrollment

20

Conditions

Macula HoleRetinal DetachmentMyopic Macular Degeneration

Interventions

Recurrent opened macular holePROCEDURE

pars plana vitrectomy + internal limiting membrane peeling + Amniotic membrane graft placement over the hole + intraocular tamponade

Eligibility

Sex: ALL
Medical Language ↔ Plain English
Inclusion Criteria: * Patient with history of opened macular hole after previous pars plana vitrectomy and internal limiting membrane (ILM) peeling for treatment of myopic macular hole were included. * Opened holes after 1 month of the surgery. * Myopic macular holes only were included (Refraction of more than \_6 D and/or axial length of more than 26 mm). Exclusion Criteria: * All other causes of macular hole (traumatic and idiopathic) * Patients with diseases that can affect visual outcome (Diabetic retinopathy, choroidal neovascularization, age-related macular disease and advanced glaucoma patients.

Locations (1)

Minia UNiversity hospital

Minya, Minya Governorate, Egypt

Outcomes

Primary Outcomes

Anatomical restoration of macular hole closure

Closure of the macular hole

Time frame: 6 months

Secondary Outcomes

Functional restoration after closure of the macular hole

Improvement of the best corrected visual acuity (BCVA)

Time frame: 6 months

Functional restoration after closure of the macular hole

Any improvement of the waves in the electrophysiological (ERG) study.

Time frame: 6 months

Data from ClinicalTrials.gov

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