Cytosponge™ for Post-Chemoradiation Surveillance of Oesophageal Cancer

Inclusion Criteria: 1. Male or female, Age \>/=16 years who 1. have undergone pre-operative CRT as treatment for oesophageal cancer and due to undergo oesophagectomy or 2. have undergone definitive CRT as treatment for oesophageal cancer 2. 4-16 weeks post completion of CRT 3. Dysphagia score 0-2 (Mellow Scale)\* 4. Able to swallow tablets 5. Physiologically fit for endoscopy 6. Written (signed and dated) informed consent 7. The patient is willing and able to comply with the protocol for the duration of the study, and scheduled follow-up visits and examinations. Exclusion Criteria: 1. Known to have oesophageal varices or stricture requiring dilatation of the oesophagus. 2. Unable to temporarily discontinue anticoagulation therapy/medication prior to their procedure\* 3. Oesophageal stent 4. Other psychological, social or medical condition, physical examination finding or a laboratory abnormality that the Investigator considers would make the patient a poor study candidate or could interfere with protocol compliance or the interpretation of study results. * Patients on anti-coagulation therapy are eligible for the study as long as they are considered suitable candidates for endoscopic biopsy (follow local hospital procedures for management of patients on anticoagulation due to undergo endoscopy). If temporary discontinuation of anticoagulation is required, this should be after consultation with the patients clinical care team.