In the Ghent University, an upgrade of the MRI-scanner used for research from Siemens Trio Tim to Siemens Prisma Fit is planned in the near future. As a change of MRI hard- and software might influence brain images, it is necessary to evaluate the images before and after the upgrade.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
OTHER
Masking
NONE
Enrollment
6
Brain imaging using magnetic resonance imaging, using several MRI sequences: structural imaging (grey matter, using T1-imaging), cerebral perfusion using arterial spin labeling), functional and effective connectivity (using resting-state functional MRI), white matter tracts (using diffusion imaging), white matter lesions (using Fluid-attenuated inversion recovery MRI (FLAIR)) and microbleeds (using Susceptibility weighted imaging (SWI))
Ghent University
Ghent, Belgium
Change in grey matter volume before versus after MRI-upgrade
Time frame: 7 months, 4 scan sessions of max 1 hour
Change in cerebral perfusion (ml/100g/min) using Arterial Spin Labeling before versus after MRI-upgrade
Time frame: 7 months, 4 scan sessions of max 1 hour
Change in arterial transit times before versus after MRI-upgrade
Time frame: 7 months, 4 scan sessions of max 1 hour
Change in functional connectivity (fc) using Resting State functional MRI before versus after MRI-upgrade
Time frame: 7 months, 4 scan sessions of max 1 hour
Change in effective connectivity using resting state functional MRI before versus after MRI-upgrade
Time frame: 7 months, 4 scan sessions of max 1 hour
Change in white matter diffusion before versus after MRI-upgrade
Time frame: 7 months, 4 scan sessions of max 1 hour
Difference in image quality of FLAIR image before versus after MRI-upgrade
Time frame: 7 months, 4 scan sessions of max 1 hour
Difference in image quality of SWI image before versus after MRI-upgrade
Time frame: 7 months, 4 scan sessions of max 1 hour
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