The purpose of this prospective, randomized, double-blind study was to compare the success rate of IAN block injection carried out with two cartridges of 2% lidocaine with 1:80000 epinephrine each combined with 0.2 ml dexamethasone versus two cartridges of 2% lidocaine with 1:80000 epinephrine each combined with 0.2 ml sterile distilled water for endodontic treatment of mandibular molars with symptomatic irreversible pulpitis.
Several investigations have been carried out to demonstrate the effect of dexamethasone added to local anesthetics in regional block injections. These investigations shown that the addition of dexamethasone to local anaesthetics may prolong the duration of anesthesia and also results in a faster onset. It is hypothesized that dexamethasone added to lidocaine may affect the success rate of inferior alveolar nerve block
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
OTHER
Masking
TRIPLE
Enrollment
100
Isfahan University of Medical Sciences
Isfahan, Iran
success of IAN Block anesthesia for the Dexamethasone group
The success of the anesthesia was defined as the tooth without pain or with mild pain according to the Heft-Parker visual analog scale (HP-VAS ≤ 54). This scale is a 170-mm horizontal line, divided into 4 categories. No pain corresponded to 0 mm; mild pain was defined as \>0 mm and 54 mm. Mild pain category included faint, weak and mild pain. A score \>54 mm and \<114 mm indicated moderate pain and included the descriptor of moderate pain. A score \>54 mm and \<114 mm indicated moderate pain and included the descriptor of moderate pain. Severe pain was defined as ≥114 mm. Severe pain was defined as strong, intense and maximum possible.
Time frame: 15 minutes after the local anesthetic injection (at time of access cavity preparation)
success of IAN Block anesthesia for the Non-dexamethasone group
The success of the anesthesia was defined as the tooth without pain or with mild pain according to the Heft-Parker visual analog scale (HP-VAS ≤ 54). This scale is a 170-mm horizontal line, divided into 4 categories. No pain corresponded to 0 mm; mild pain was defined as \>0 mm and 54 mm. Mild pain category included faint, weak and mild pain. A score \>54 mm and \<114 mm indicated moderate pain and included the descriptor of moderate pain. A score \>54 mm and \<114 mm indicated moderate pain and included the descriptor of moderate pain. Severe pain was defined as ≥114 mm. Severe pain was defined as strong, intense and maximum possible.
Time frame: 15 minutes after the local anesthetic injection (at time of access cavity preparation)
initial pain
rating the pain on Heft-Parker visual analog scale. This scale is a 170-mm horizontal line, divided into 4 categories. No pain corresponded to 0 mm; mild pain was defined as \>0 mm and 54 mm. Mild pain category included faint, weak and mild pain. A score \>54 mm and \<114 mm indicated moderate pain and included the descriptor of moderate pain. A score \>54 mm and \<114 mm indicated moderate pain and included the descriptor of moderate pain. Severe pain was defined as ≥114 mm. Severe pain was defined as strong, intense and maximum possible.
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Time frame: Baseline