Patients scheduled for Thoracic Endovascular Aortic Repair (TEVAR) surgery will have transthoracic echocardiography evaluation of left ventricle diastolic function during the perioperative period.
Patients undergoing TEVAR surgery are a high risk group of developing perioperative cardiovascular complications. Left ventricle diastolic dysfunction is common in this group of patients because of the prevalence of risk factors: \> 60 years old, hypertension, smoking history and diabetes. Because of many predisposing factors that occur during the surgery: stress respond, fluid shifts, anaesthesia and mechanical ventilation. Deterioration of the diastolic function is likely to occur in perioperative period In this study, the investigators will evaluate change in left ventricle diastolic function as a marker for early detection of a myocardial failure in patients scheduled for an elective TEVAR surgery. The examination will be performed preoperatively, shortly after the surgery and 24 hours after the surgery. Aim: The aim of the study is to evaluate the diastolic function of left ventricle in perioperative period after high risk surgery. This may provide a valuable information in preoperative risk stratification and postoperative therapy guidance.
Study Type
OBSERVATIONAL
Enrollment
30
Medical University Of Warsaw
Warsaw, Mazovian, Poland
Change in left ventricle diastolic function in time
Echocardiographic assessment of change in left ventricle diastolic function repeated in time intervals: Baseline before the surgery, 2 and 24 hours after the surgery
Time frame: Baseline, 2 hours and 24 hours
Change in biochemistry markers: troponins
Assessment of change in level of troponins. Baseline before the surgery, 2 and 24 hours after the surgery
Time frame: Baseline, 2 hours and 24 hours
Change in biochemistry markers: brain natriuretic peptide
Assessment of change in level of brain natriuretic peptide. Baseline before the surgery, 2 and 24 hours after the surgery
Time frame: Baseline, 2 hours and 24 hours
Change in left ventricle systolic function
Echocardiographic assessment of change in left ventricle systolic function repeated in time intervals: Baseline before the surgery, 2 and 24 hours after the surgery
Time frame: Baseline, 2 hours and 24 hours
Hemodynamic parameters: Heart rate
Heart rate during echocardiography evaluation.
Time frame: Baseline, 2 hours and 24 hours
Hemodynamic parameters: Systolic and diastolic pressure
Systolic and diastolic pressure measurements during echocardiography evaluation. Record vasopressors requirement.
Time frame: Baseline, 2 hours and 24 hours
Fluid balance
Monitoring of diuresis hourly, fluid losses and fluids intake
This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.
Time frame: 72 hours
Kidney function
Monitoring of glomerular filtration rate and requirement for a dialysis daily
Time frame: 72 hours
Length of stay in hospital
Documentation of length of stay in hospital since the surgery
Time frame: up to 14 days
Mortality
Documentation of in-hospital mortality and 30 days mortality
Time frame: up to 30 days