A Comparison Between Child-Pugh and Albumin-Bilirubin Scores

Huazhong University of Science and Technology230 enrolled

Overview

To compare Child-Pugh and Albumin-Bilirubin scores in patients with spontaneous rupture of hepatocellular carcinoma

To compare Child-Pugh and Albumin-Bilirubin scores in patients with spontaneous rupture of hepatocellular carcinoma. And to determine which is better in predicting long-term survival and short-term survival.

Study Type

OBSERVATIONAL

Enrollment

230

Conditions

Rupture, Spontaneous Rupture Liver Hepatocellular Carcinoma Hepatic Impairment

Interventions

Liver resectionPROCEDURE

Liver resection was comprised of single or multiple liver resections aiming to excise all macroscopic tumors.

Transcatheter arterial embolizationOTHER

Transcatheter arterial embolization or transcatheter arterial chemoembolization can localize the bleeding point and provide interventional embolization.

Eligibility

Sex: ALLMin age: 15 YearsMax age: 76 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Be diagnosed as hepatocellular carcinoma pathologically; had a tumor rupture confirmed by Intraperitoneal exploration or clinical signs and symptoms in combination with imaging examination. Exclusion Criteria: * Be diagnosed as not hepatocellular carcinoma pathologically；had repeated transcatheter arterial chemoembolization(TACE) or a long history (more than 1 year) of cancer treatment; loss of follow up or without complete data.

Outcomes

Primary Outcomes

Overall survival of all patients

Overall survival of all patients among different Child-Pugh and albumin-bilirubin scores

Time frame: 5 years

Secondary Outcomes

Short-term mortality of all patients

Ninety-day mortality of all patients among different Child-Pugh and albumin-bilirubin scores

Time frame: Ninety days

Short-term mortality of surgical subgroup

Ninety-day mortality of the surgical subgroup among different Child-Pugh and albumin-bilirubin scores

Time frame: Ninety days

Short-term mortality of non-surgical subgroup

Ninety-day mortality of the non-surgical subgroup among different Child-Pugh and albumin-bilirubin scores

Time frame: Ninety days

Data from ClinicalTrials.gov

This platform is for informational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional.