Pilot Cohort Study of Rb-82 Myocardial PET Imaging to Evaluate Coronary Microvascular Dysfunction in Men With Prostate Cancer Receiving Androgen-Deprivation Therapy

Inclusion Criteria: * Either clinically localized prostate cancer or biochemically-recurrent prostate cancer patients who are planned for at least 6 months ADT with a GnRH agonist and curative-intent radiation therapy per their oncologic providers. * Over 50 years of age. Calculated 10-year Framingham General Cardiovascular Risk Score of ≥10% at the time of planned initiation of ADT. * Patients must be able to read and understand English. * Participants must sign the informed consent form. Exclusion Criteria: * Prior treatment with GnRH agonist therapy. * History of active asthma or other reactive airway disease. * Ischemic cardiac event (myocardial infarction, unstable angina) within the preceding 6 months.