Despite technological advancements directed towards the diagnosis of peripheral pulmonary lesions, an optimal approach has yet to be designed. One significant barrier for the bronchoscopic biopsy of peripheral lesions is the ability to reliably locate peripheral lesions in an efficient manner. The majority of the published literature regarding peripheral lesion biopsy has used diagnostic yield as the primary endpoint. Based on this data, it is unclear if non-diagnostic procedures are due to the inability to locate peripheral lesions, or due to the inability to successfully biopsy lesions once located using currently available instruments. This study will evaluate the bronchoscopists' ability to locate peripheral pulmonary lesions by using a conventional chest computed tomography (CT) scan as a reference and a virtual bronchoscopic navigational system, if needed, for the localization of peripheral pulmonary lesions.
Study Type
INTERVENTIONAL
Allocation
NA
Purpose
TREATMENT
Masking
NONE
-Standard of care
-Virtual bronchoscopic navigation system
-Standard of care
Localization of peripheral pulmonary lesions as confirmed using radial probe endobronchial ultrasound
Time frame: At the time of bronchoscopy (day 1)
Rate of lesion localization using a conventional chest CT as a reference only
Time frame: At the time of bronchoscopy (day 1)
Rate of lesion localization using virtual bronchoscopic navigation if needed (failed lesion localization using conventional chest CT only)
Time frame: At the time of bronchoscopy (day 1)
Time to localization of peripheral pulmonary lesions
Time frame: At the time of bronchoscopy (day 1)
Diagnostic yield of procedures
-Diagnostic yield based on final cytology and/or histopathology will be determined from the results of the bronchoscopy. A biopsy that results in a specific diagnosis, either malignant or benign, that adequately explains the clinical scenario as determined by the treating physician, will be considered truly positive.
Time frame: At the time of bronchoscopy (day 1)
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