Impact of Renal Replacement Therapy on Coagulation Profile of Patients with Acute Renal Failure

University Hospital, Brest14 enrolled

Overview

Renal failure and high plasmatic level of urea have been associated with an increased risk of hemorrhage in surgical patients. There is only sparse data on the impact of renal replacement therapy on homeostatic parameters. The aim of this study is to describe potential changes in homeostatic parameters before and after renal replacement therapy.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Acute Renal Failure Hemorrhage Coagulation Disorder

Eligibility

Sex: ALLMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * critically ill patients * acute renal failure * renal replacement therapy * plasmatic urea \> 20 Exclusion Criteria: * chronic renal failure * platelet count less than 80 Giga * V factor less than 70%

Locations (1)

CHRU de Brest

Brest, France

Outcomes

Primary Outcomes

visco elastometry

ROTEM (Rotational Thromboelastometry)

Time frame: Change in ROTEM parameters from baseline to after renal replacement therapy

Data from ClinicalTrials.gov

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