Determination of the Independent Effects of Beetroot Juice Components, Dietary Nitrate and Antioxidants, on Exercise Tolerance and Health Benefits in Individuals With Obesity

University of Alabama at Birmingham16 enrolled

Overview

The purpose of this study is to assess the effects of acute beetroot juice supplementation on exercise performance and cardiometabolic health in obese individuals with secondary cardiometabolic complications. Additionally, we will determine if the ergogenic health benefits of beetroot juice is due to the nitric oxide compound within the product, the antioxidant compound within the product, or a combination of the two compounds.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

SINGLE

Enrollment

Conditions

Metabolic Disease Obesity Exercise

Interventions

Eligibility

Sex: ALLMin age: 18 YearsMax age: 40 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: * BMI ≥ 30 kg/m2 * Able to perform exercise testing on a cycle ergometer Exclusion Criteria: * Currently taking medications know to affect cardiovascular or respiratory function * Currently supplementing with an antioxidant compound * Current smoker * Currently taking antibiotics * Not willing to abstain from mouthwash use * Currently participating in regular physical activity

Outcomes

Primary Outcomes

Time to Exhaustion

Time frame: A Time to Exhaustion Test will be conducted on each participant a total of four times throughout their participation in the study. This will take place approximately 2.5 hours post ingestion of the dietary supplement they are randomized to at each visit.