This intervention study investigates the effects of various kale preparations (dietary supplements) on lipid status parameters. Within the study period of 8 weeks, three blood withdrawals are planned (week 0, 4 and 8) for the volunteers. Lipid status parameters (total cholesterol, HDL cholesterol, LDL cholesterol, triacylglycerides) will be determined in blood. There is a correlation between contents of LDL cholesterol, total cholesterol and triacylglycerides and the risk for cardiovascular diseases (CVD). In contrast, a high content of HDL cholesterol is correlated with a lower risk for CVD. In addition, the contents of apolipoprotein A1 and apolipoprotein B will be analysed.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
QUADRUPLE
Enrollment
40
Effect of kale preparation kale powder on lipid status
Effect of kale preparation kale extract on lipid status
Effect of kale preparation flavonoid extract on lipid status
Effect of placebo on lipid status
Friedrich Schiller University, Institute iof Nutritional Science
Jena, Thuringia, Germany
RECRUITINGChange of lipid status parameters
total cholesterol, HDL cholesterol, LDL cholesterol
Time frame: weeks 0, 4 and 8
Change of apolipoproteins
apolipoprotein A1 and apolipoprotein B
Time frame: weeks 0, 4 and 8
Change of antioxidant capacity
lipophilic antioxidant capacity (L-TEAC)
Time frame: weeks 0, 4 and 8
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