This study investigates the effect of various forms of upper extremity exercise on postprandial glycemia and lipemia in persons with spinal cord injury (SCI). Participants are measured at rest and fed a standardized meal following seated rest (CON), moderate intensity continuous arm cycling (MICT), high intensity interval arm cycling (HIIT), and circuit resistance exercise (CRT) matched for exercise energy expenditure.
Study Type
INTERVENTIONAL
Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
NONE
Enrollment
10
Seated rest
Arm cycling at a continuous power output
Arm cycling at power outputs that vary between high and low intensity intervals
Lois Pope Life Center
Miami, Florida, United States
Postprandial insulin sensitivity
Measured by insulin incremental area under the curve (iAUC).
Time frame: 2.5 hr
Postprandial insulin sensitivity
Measured by "ISIMatsuada" insulin sensitivity index. This index is calculated based on the ratio of blood glucose and insulin.
Time frame: 2.5 hr
Lipemia
Measured by blood concentrations of triglycerides.
Time frame: 2.5 hr
Carbohydrate use
Whole-body rates of carbohydrate oxidation, as determined by open-circuit indirect calorimetry.
Time frame: 2.5 hr
Fat use
Whole-body rates of fat oxidation, as determined by open-circuit indirect calorimetry.
Time frame: 2.5 hr
Fasted insulin sensitivity
Measured by "HOMA-2" model. This model is calculated based on the ratio of blood glucose and insulin.
Time frame: Baseline
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Alternating between six upper extremity resistance maneuvers interspersed with low-resistance/high-speed arm cycling.
A liquid meal consisting of 600 kcal comprised of 50% carbohydrate, 35% fat, and 15% protein (by kcal).