Overnight Pain Treatment Investigating Opioids vs. Nonopioids

University of Pennsylvania70 enrolled

Overview

The purpose of this study is to compare maximum pain scores between patients seeking induced abortion and requiring cervical preparation with osmotic dilators. Patients will be randomized to receive prescription for ibuprofen alone or to receive prescription for ibuprofen + oxycodone for overnight pain management after cervical preparation with osmotic dilators. Data collected in-person and through a text-messaging platform.

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Abortion Second Trimester

Interventions

Ibuprofen 600 mgDRUG

Ibuprofen 600mg prescription, to be taken 1 tablet as needed every 6 hours for pain.

OxyCODONE 5 Mg Oral TabletDRUG

Oxycodone 5mg Oral Tablet prescription, to be taken 1-2 tablets as needed every 6 hours for pain.

Eligibility

Sex: FEMALEMin age: 18 Years

Medical Language ↔ Plain English

Inclusion Criteria: * English-speaking women * 18 years or older * Access to cell phone with text-messaging capability/data * Receiving cervical preparation for induced abortion * Able to complete baseline survey on smartphone/tablet at screening visit Exclusion Criteria: * History of opioid or alcohol abuse * Contraindications or allergy to ibuprofen * Contraindications or allergy opioid medications * Seeking uterine evacuation for premature preterm rupture of membranes or advanced - cervical dilation or intrauterine fetal demise

Locations (1)

Hospital of the University of Pennsylvania

Philadelphia, Pennsylvania, United States

Outcomes

Primary Outcomes

Maximum Pain Score

Numerical Rating Scale (NRS) pain score (scale range 0-10, with a 0 meaning "no pain" and 10 meaning the "worst possible pain")

Time frame: 24 hours

Data from ClinicalTrials.gov

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