Role of Interferon-gamma 1-b (IFN-γ) on Cells of the Innate Immune System: Functional, Biochemical and Gene Expression Studies in Patients With Chronic Granulomatous Disease

Inclusion Criteria: * Current treatment with IFN-γ or intent to treat with this drug * Acute infections resolved * Subject is off treatment medications * Women of childbearing potential must have: * a negative urine beta-HCG, and * be willing to practice two forms of effective contraception for the duration of study participation Exclusion Criteria: * Pregnancy, * Breast-feeding, or * Unwillingness to use effective contraception * Recent vaccination (within the last fourteen days) * Current infection or acute health condition requiring treatment * Chronic inflammatory complications of CGD including: * gastric outlet or urinary tract obstruction, * pleuritis, * pericarditis, * inflammatory bowel disease, or * colitis requiring treatment. * Un-associated chronic lung, liver, kidney, or cardiac disorders requiring active treatment