Evaluation of the impact of the introduction of multiplex PCR panels on the clinical management of patients with gastroenteritis at the University Hospital of Lausanne, Switzerland.
Gastrointestinal multiplex PCR panels have been introduced in clinical practice several years ago, but the impact on the management of patients is yet unknown. The investigators are interested to evaluate if the multiplex PCR panels introduced at the University Hospital of Lausanne in July 2017 modified the usual medical care and in particular the prescription of anti-infectious treatments. The high sensitivity of the multiplex PCR panels should allow a more precise diagnosis of the etiology of the gastrointestinal symptoms of the patients than the traditional methods of stool culture and microscopy. The investigators expect therefore to observe a modification of the proportion of patients receiving anti-infectious treatment, but it is uncertain if it will lead to an increase or a decrease in the use of antibiotics. On one hand antibiotics could be prescribed more often due to a greater and faster detection of enteropathogens. On the other hand antibiotics could be prescribed less often due to more precise diagnosis, showing that viruses and certain bacteria do not require antibiotic treatment.
Study Type
OBSERVATIONAL
Enrollment
210
The study will evaluate the change in medical management with the replacement of traditional stool investigations (microscopy and culture) by the new gastrointestinal multiplex PCR panels
Department of Outpatient Care and Community Medicine, University Hospital of Lausanne
Lausanne, Switzerland
Prescription of antibiotics
Number of patients receiving a prescription of antibiotics depending on the type of investigation
Time frame: Within 1 week of availability of stool result
Pathogens identified
Number and types of pathogens identified depending on the type of investigation
Time frame: 1 day
Number of PCR tests requested.
Number of patients for whom one, two or more PCR tests were requested.
Time frame: 1 month
Additional investigations
Number of patients who underwent additional investigations within 1 week after reception of the results of the initial investigations
Time frame: 1 week
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