The aim of the study is to develop a prognostic index for elderly patients with newly diagnosed cHL starting from a prospective observational study of consecutive cases registered after the completion of the Comprehensive Geriatric Assessment (CGA)
The aim of the study is to develop a prognostic index for elderly patients with newly diagnosed cHL starting from a prospective observational study of consecutive cases registered after the completion of the Comprehensive Geriatric Assessment (CGA) Prospective data collection study of a consecutive series of newly diagnosed elderly cHL patients undergoing CGA before any therapy with the use of ADL, IADL and CIRS-G. Patients who will be considered not eligible to receive treatment or to be given only palliative therapy after CGA assessment are eligible for the study. Patients will be screened and restaged according to clinical practice instrumental and laboratory assessments timing and type of examinations.
Study Type
OBSERVATIONAL
Enrollment
400
Prospective data collection with the aim to to develop a prognostic index for elderly patients with newly diagnosed cHL
OS
Overall survival (OS). From the date of diagnosis to the date of last observation or death from any cause
Time frame: June 2018-December 2025 (7.5 years)
PFS
Progression Free Survival (PFS): From the date of diagnosis to the last follow-up, or to one of the following events: disease progression during treatment, or relapse, or death from any cause.
Time frame: June 2018-December 2025 (7.5 years)
FFS
Failure Free Survival (FFS). From the date of diagnosis to to any treatment failure including disease progression, or discontinuation of treatment for any reason, (eg, disease progression, toxicity, patient preference, initiation of new treatment), or death from any cause.
Time frame: June 2018-December 2025 (7.5 years)
Response initial therapy
Response initial therapy: Rate of complete remission (CR) after chemotherapy +/-RT, according to Cheson 2007
Time frame: June 2018-January 2024 (5.5 years, 6-7 month after the enrolment)
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SC Ematologia AO SS. Antonio e Biagio e C. Arrigo
Alessandria, Italy
NOT_YET_RECRUITINGUniversità Politecnica delle Marche - Clinica di Ematologia
Ancona, Italy
RECRUITINGAzienda Ospedaliera S. Giuseppe Moscati - S.C. Ematologia e Trapianto emopoietico
Avellino, Italy
NOT_YET_RECRUITINGCentro Riferimento Oncologico - S.O.C. Oncologia Medica A
Aviano, Italy
RECRUITINGAOU Policlinico Consorziale - U.O. Ematologia con Trapianto
Bari, Italy
RECRUITINGOspedale "Monsignor Raffaele Dimiccoli" - Ematologia
Barletta, Italy
NOT_YET_RECRUITINGASST Spedali Civili di Brescia - Ematologia
Brescia, Italy
RECRUITINGOspedale Businco - Ematologia
Cagliari, Italy
NOT_YET_RECRUITINGUniversità Cattolica del Sacro Cuore - Ematologia
Campobasso, Italy
NOT_YET_RECRUITINGOspedale di Castelfranco Veneto - Ematologia
Castelfranco Veneto, Italy
RECRUITING...and 34 more locations