This is a retrospective, descriptive study that involves de-identified data consisting of weight changes, pertinent vital signs and laboratory values influenced by body weight, and healthcare utilization of patients prescribed lorcaserin at The Center for Weight Management at the Scripps Clinic in San Diego, CA.
All patients who initiated treatment with Lorcaserin during the review period will undergo chart review. The primary endpoint will be weight change in patients on Lorcaserin and average duration of Lorcaserin treatment over time (up to 1 year). Secondary endpoints will include changes in vital signs, liver function, glucose, and lipids. In addition, time on treatment, reasons for discontinuation of medication, and changes in healthcare utilization (to include inpatient and outpatient utilization) will be examined. This is a retrospective, one-arm observational study that will include chart reviews of 157 patients who have been treated in the clinic.
Study Type
OBSERVATIONAL
Enrollment
157
Treatment initiation with Lorcaserin
Scripps Whittier Diabetes Institute
San Diego, California, United States
Weight change - in pounds
Change in weight with Lorcaserin treatment
Time frame: Up to 1 year of medication use
Duration of Use - in weeks
Average duration of treatment with Lorcaserin
Time frame: Up to 1 year of medication use
Change in heart rate
Assessment of change heart rate (bpm)
Time frame: Up to 1 year of medication use
Change in blood pressure
Assessment of change in both systolic and diastolic blood pressure (mmHg)
Time frame: Up to 1 year of medication use
Change in lipid levels
Assessment of change in lab values for total cholesterol, LDL, HDL and Triglycerides
Time frame: Up to 1 year of medication use
Change in liver enzymes
Assessment of change in lab values for AST and ALT
Time frame: Up to 1 year of medication use
Change in glucose values
Assessment of change in lab values for fasting glucose and hemoglobin A1c
Time frame: Up to 1 year of medication use
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