Trendelenburg Maneuver Predicts Fluid Responsiveness in Patients With Extracorporeal Membrane Oxygenation (TEMPLE)

Shanghai Zhongshan Hospital40 enrolled

Overview

The purpose of the study is to verify the efficacy of using trendelenburg maneuver to predict fluid responsiveness in patients with extracorporeal membrane oxygenation

Study Type

INTERVENTIONAL

Allocation

Purpose

TREATMENT

Masking

NONE

Enrollment

Conditions

Extracorporeal Membrane Oxygenation

Interventions

Trendelenburg ManeuverDIAGNOSTIC_TEST

In the Trendelenburg position, the body is laid supine, or flat on the back with the feet higher than the head by 15-30 degrees. The venous return increases in the trendelenburg position which in turn increases the stroke volume.

Eligibility

Sex: ALLMin age: 18 YearsMax age: 80 Years

Medical Language ↔ Plain English

Inclusion Criteria: * patients with ECMO and mechanical ventilator support * hypotension (MAP\<65mmHg) * required volume expansion by clinical judgement of the intensivists Exclusion Criteria: * severe hypotension with high dose of vasopressors * severe valve regurgitation * cardiac arrhythmia

Locations (1)

Zhongshan hospital, Fudan university

Shanghai, China

RECRUITING

Outcomes

Primary Outcomes

responders

responders are defined by stroke volume increases over 15% after volume expansion of 500ml crystalloid

Time frame: within 1 minute after volume expansion

nonresponders

nonresponders are defined by stroke volume increases less than 15% after volume expansion of 500ml crystalloid

Time frame: within 1 minute after volume expansion

Central Contacts

Guo-wei Tu, Doctor

CONTACT

86-021-64041990 tu.guowei@zs-hospital.sh.cn

Data from ClinicalTrials.gov

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