Agitation and Aggressivity in Alzheimer's Disease Patients: A Cohort Study

Inclusion Criteria: 1256/5000 * Patient with AD according to NINCDS-ADRDA criteria with or without cerebrovascular component at all stages of the disease. * Patient with agitation / aggression (A / A) type SPCDs, assessed with a score ≥ 4 of at least 1 of the A / A domains, disinhibition, irritability and / or aberrant motor behavior of the NPI scale, with a score frequency ≥2 during the inclusion visit. * Participation agreement signed by the patient or, in the event of the patient's incapacity, by his / her legal representative or, as the case may be, by the person of trust or family. The patient's ability to sign informed consent is evaluated by a clinician experienced in the field of dementia. * Patient with social security If the patient lives at home: * Presence of a clearly identified primary caregiver: Person from the entourage of the patient who assumes the main part of the care (at least 2 hours at least 3 times during the week) able to complete the questionnaires and to evaluate the patient. * Availability and agreement of the carer to accompany the patient during consultations. If the patient lives in an institution: • He / she must have been there for at least 2 months before inclusion. Exclusion Criteria: 745/5000 * Brain pathology (other than AD) that may be the cause of dementia: extensive cerebrovascular disease, Parkinson's disease, Lewy body dementia, frontotemporal dementia, brain trauma. * A / A secondary to concomitant medications, or to a medical or psychiatric condition * Concurrent major depressive episode (DSM-IV). * Psychotic symptoms of delirium type and hallucination clinically significant (score ≥ 4 field delusions and / or hallucinations of the NPI scale). * Presence of concomitant pathologies preventing participation in the study (testing and / or study visits). * Concurrent participation in another research that may influence the testing of our study.