Phase 4 observational cohort study to characterize the treatment patterns and effects of avatrombopag use in patients with thrombocytopenia associated with chronic liver disease who are either undergoing, or have already undergone, a procedure.
Data (e.g. type of procedure, platelet count, etc.) will be collected retrospectively or prospectively from patient visits occurring within approximately 7 calendar days prior to the first dose of avatrombopag, on Procedure Day, on Discharge Day, and from any clinic visit performed up to 30 days post-procedure. All treatment decisions and clinical assessments will be at the discretion of the treating physician per routine medical care and are not mandated by study design or protocol.
Study Type
OBSERVATIONAL
Enrollment
50
Avatrombopag dosing will be determined by the treating physician in conjunction with the FDA-approved package insert.
Change in platelet count
Time frame: Up to 8 days after the last dose of avatrombopag.
Proportion of patients who received a platelet transfusion
Time frame: From the first dose of avatrombopag to up to 15 days after the last dose of avatrombopag
Occurrence of adverse events
Time frame: From the first dose of avatrombopag to up to 30 days after the last dose of avatrombopag
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Dova Site
Chandler, Arizona, United States
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Lancaster, California, United States
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Los Angeles, California, United States
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Palm Springs, California, United States
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Pasadena, California, United States
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San Clemente, California, United States
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San Diego, California, United States
Dova Study Site
San Diego, California, United States
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Aurora, Colorado, United States
Dova Study Site
Englewood, Colorado, United States
...and 31 more locations