There are no studies evaluating the effect of aging on hemostasis of preeclamptic patients. Additionally, although there are some studies that establish normal reference values for TEG profiles in healthy term pregnant patients, conflicting results have been found in preeclampsia. Reference values are important to establish baseline parameters in cases of pre-eclampsia complicated by postpartum hemorrhage. The investigators will evaluate reference values for TEG in postdelivery preeclamptic patients and the difference between vaginal delivery and cesarean section.
After approval by the Institutional Review Board and informed consent from participants, the investigators are obtaining blood samples for TEG processing, from pregnant patients admitted to the maternity unit of Augusta University Medical Center. Patients are being classified in 2 groups: term pregnant patients with diagnosis of pre-eclampsia who undergo cesarean section and those having spontaneous vaginal delivery. Each group will be divided into subgroups according to maternal age: 18-25 years, 26-35 years, \>36 years. Pre-eclampsia is defined and classified according to the definitions of the American College of Obstetricians and Gynecologists published in 2013.
Study Type
OBSERVATIONAL
Enrollment
30
Blood sample processing for thromboelastogram
Augusta University
Augusta, Georgia, United States
R time
Reaction time of whole blood
Time frame: 10 minutes
K time
Activation time
Time frame: 10 minutes
Maximum amplitude
Amplitude in relation to platelet count and function
Time frame: 10 minutes
LY-30
Lysis at 30 minutes
Time frame: 30 minutes
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