In this study, the primary objective was to estimate the minimum effective volume of bupivacaine 0.5% resulting in successful block in 90% of patients (MEV90) for ultrasound-guided retroclavicular approach to infraclavicular brachial plexus block.
A "biased coin up-and-down sequential design" will be applied to assess the minimum effective volume in 90% of patients for the retroclavicular brachial plexus block. The first subject received 25 ml 0.5% bupivacaine . Each subsequent patient received a dose that depended on the response of the previous one. If the previous block is successful, the block will be performed either by a reduction of the volume by 2.5 ml with a probability ß = 0.11 or by a same dose of the previous one with a probability 1-ß = 0.89 in the next patient.
Study Type
OBSERVATIONAL
Enrollment
45
The determination of MEV90 and its 95% confidence interval (CI) will be based on a "biased coin up-and-down sequential design
Antalya Training and Research Hospital
Antalya, Turkey (Türkiye)
The minimum effective volume of bupivacaine 0.5% resulting in successful block in 90% of patients (MEV90)
The determination of MEV90 and its 95% confidence interval (CI) will be based on a "biased coin up-and-down sequential design
Time frame: 30 minutes
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