Severe and Transient Hypoxemia During Selective Intra-arterial Chemotherapy for Retinoblastoma in Children: Evaluation of the Right-sided Heart Function.

Christian Kern50 enrolled

Overview

Children having selective ophthalmic artery chemotherapy for retinoblastoma under general anaesthesia may experience troubles during the procedure. The troubles are transient, may be severe and include hypoxemia, hypotension and bradycardia. All children having such trouble always fully recovered without any sequelae or prolonged length of stay. The investigators suspect that these phenomenons are caused by transient pulmonary hypertension.The objective is to see whether transient pulmonary hypertension and right-sided heart failure is present during theses phenomenon by trans-thoracic echocardiography.

Study Type

OBSERVATIONAL

Enrollment

Conditions

Retinoblastoma

Interventions

Trans-thoracic echocardiographyDIAGNOSTIC_TEST

Trans-thoracic echocardiography

Eligibility

Sex: ALLMax age: 6 Years

Medical Language ↔ Plain English

Inclusion Criteria: * Retinoblastoma requiring selective ophthalmic artery chemotherapy under general anaesthesia Exclusion Criteria: * Obesity * pre-existing significant heart or pulmonary disease.

Outcomes

Primary Outcomes

Identification of pulmonary hypertension and/or right-sided heart failure (systolic arterial pulmonary pressure and visual function of the right ventricle is measured)

Time frame: Perioperative.