Nutrient Supplementation Influences Mitochondria Adaptation

University of Aarhus24 enrolled

Overview

Twenty-four well trained runners (VO2max 60.73.7 ml O2 Kg-1 min1) completed a six week block randomized controlled intervention period. Subjects were randomly assigned to either PRO-CHO or CHO and matched in pairs for gender, age, VO2max, training and performance status. The PRO- CHO group ingested a protein beverage (0.3g kg-1) before and protein-carbohydrate beverage (0.3g protein kg-1 and 0.1g carbohydrate kg-1) after each exercise session. The CHO group ingested energy matched carbohydrate. Post-absorptive muscle biopsies were obtained pre and post intervention for analysis HAD, CS and PGC-1. Subjects completed two physical tests 6 km performance test (pre, week 1 and week 6) and aVo2max test (pre and post intervention).

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

OTHER

Masking

SINGLE

Enrollment

Conditions

Performance Nutrition Protein

Interventions

Eligibility

Sex: ALLMin age: 18 YearsMax age: 55 YearsHealthy volunteers:

Medical Language ↔ Plain English

Inclusion Criteria: 1. maximal oxygen uptake (VO2max) of \>50ml O2 kg-1 min-1 for women and \>55ml O2 kg-1 min-1 for men, 2. running at least 3 times a week and 3. running being the primarily training form Exclusion Criteria: 1. use of medicine 2. diagnosed metabolic diseases 3. injuries which hindered running and body mass index (BMI) \< 25 kg m-2

Locations (2)

Aarhus University, Department for Public Health, Section for Sport Science

Aarhus, Denmark

Sport Science, Department of Public Health, Aarhus University

Aarhus, Denmark