Effect of Anaesthesia on ER Stress in Cancer Patients

Konkuk University Medical Center53 enrolled

Overview

Investigate the change in endoplasmic reticulum stress after cancer surgery according to different anaesthetics including propofol and sevoflurane.

We hypothesize propofol and sevoflurane based anesthesia would show different pattern of endoplasmic reticulum stress after cancer surgery in patients with cancer

Study Type

INTERVENTIONAL

Allocation

RANDOMIZED

Purpose

BASIC_SCIENCE

Masking

QUADRUPLE

Enrollment

Conditions

Endoplasmic Reticulum Stress

Interventions

PropofolDRUG

propofol based anesthesia

SevofluraneDRUG

sevoflurane based anesthesia

Eligibility

Sex: FEMALEMin age: 20 Years

Medical Language ↔ Plain English

Inclusion Criteria: \- patients with cancer Exclusion Criteria: * age under 19 years old * allergy history to propofol or sevoflurane * history of previous cancer

Locations (1)

Konkuk University Medical Center

Seoul, South Korea

Outcomes

Primary Outcomes

Change in endoplasmic reticulum stress

Time frame: baseline, postoperative 1 hours and 24 hours

Data from ClinicalTrials.gov

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